Applications and workflows on the CGC: an update on available pipelines and how to run a GWAS on the cloud
This May, the CGC Webinar Series features a talk by Drs. Zélia Worman and Rowan Beck from Seven Bridges. Zelia is a Program Manager and Rowan is a Community Engagement Manager, both working on the Cancer Genomics Cloud.
In this upcoming webinar, they will talk about the new tools and datasets that are available on the Cancer Genomics Cloud (CGC), and will demonstrate how to run a Genome-wide association study (GWAS) on the CGC. With the growth of large-scale genomics, it’s hard to keep track of all the different tools and gold standards to analyze a particular dataset. The CGC not only hosts petabytes of public data integrated with the Cancer Research Data Commons ecosystem, but also provides the tools and pipelines to analyze it. As more data is added to the CGC, the public apps gallery has been updated to meet our users’ needs. In this webinar, we will highlight the new and updated applications and workflows to run variant calling, epigenetic studies, and long sequence reads, among others. We will also demonstrate how to perform a GWAS using the power of cloud computing.
Using the CGC, users have access to public genome cancer data without any requirement of software installation or system configuration. This setup provides access to comprehensive pan-cancer genome analyses and facilitates data mining in wide research areas, such as therapeutic discovery process. As GWAS are fairly computationally intensive, using the cloud can provide an accessible platform for all researchers, particularly ones that do not have access to a high performance computing platform.
More about the speakers
Rowan Beck, PhD
Rowan’s primary interests lie at the intersection of public health and large scale “omics” analyses. She earned her PhD in 2019 from the University of North Carolina at Chapel Hill. Her graduate work focused on the identification of microRNAs and other regulatory mechanisms that underpin the association between environmental toxicant exposure and diabetes phenotypes. Prior to joining Seven Bridges, Rowan worked as a toxicologist at Reynolds American to evaluate the chemical, biological, and toxicological data generated across numerous products, materials, ingredients, technologies, and manufacturing processes.
Zélia Worman, PhD
Prior to Seven Bridges, Zelia was a scientific program manager for the Translational Research Institute for Space Health (TRISH), where she provided recommendations on research funding and strategies, peer-review procedures, and logistics. Zelia’s research interests are on human population genomics, space health, and transposable elements.
Zélia was born in Porto, Portugal where she received her bachelors in Biochemistry and PhD in Biodiversity, Genetics and Evolution from the University of Porto. Zelia was a postdoctoral fellow at the University of Pittsburgh and Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) .
MORE ABOUT US AND THE CGC
Seven Bridges is the leading biomedical data company, specializing in software and data analytics to drive public and private healthcare research. We deliver end-to-end bioinformatic solutions — including access to datasets, analytic workflows and algorithms, cloud-computing infrastructure, and scientific support — that speed the path from raw experimental data to new treatments and diagnostics.
The Cancer Genomics Cloud (CGC), powered by Seven Bridges and funded by the National Cancer Institute, is a flexible cloud resource platform that enables storage, analysis, and computation of large cancer datasets in the cloud. Since its launch in 2016, the platform has been continuously iterated with new applications and features to address the exponential growth and diversity of complex datasets. With the CGC, any user with an account can easily access petabytes of data, share it, analyze and use the computational power of the cloud without having to learn how to program and get familiar with several different data portals.