Topic for August: The Exploration of Pan-Cancer Dysregulated Pathways and PolyTherapy AI

This August, the CGC Webinar Series features a talk by Margaret Liñán, MPH MS, Bioinformatics Consultant with the College of Health Solutions, Arizona State University.

In this webinar, Margaret will discuss her translational bioinformatics research in collaboration with Dr. Valentin Dinu, an Associate Professor of Biomedical Informatics and the Principal Investigator of the Translational Genomics Lab at the College of Health Solutions at Arizona State University. Their collaborative research includes two previous pan-cancer studies: 1) Detecting and ranking mRNA dysregulated pathways using the Dinu Lab’s Pathways of Topological Rank Analysis (PoTRA) tool (Bioconductor) with HTSeq FPKM normalized mRNA data from the TCGA, and 2) identifying drivers of rank dispersion in mRNA mediated dysregulated pathways from invasive breast cancer. Finally, the most recent study, PolyTherapy AI, is a multi-institutional and multi-national collaboration with industry that will be developed as an interactive artificial intelligence platform for multi-omics combination drug treatment.

Margaret Liñán, MPH MS, Bioinformatics Consultant

About our Featured Speaker:

Margaret is a Bioinformatics Consultant, currently collaborating with Dr. Valentin Dinu’s (PI) Translational Genomics Lab at the College of Health Solutions – Arizona State University, and others (academia/industry) on the PolyTherapy AI project. Margaret has previously worked in academia as a Computational Research Scientist and Consultant at the Icahn School of Medicine at Mount Sinai and in the biotechnology industry as a Bioinformatics Deep Learning Scientist. She has also worked as a bioinformatics research trainee in the Department of Health Sciences Research at the Mayo Clinic where she successfully executed a large-scale pathway analysis and graph networks project.